Hormone Therapy FAQ: Compounded BHRT, Costs, Safety, and More

Hormone Therapy FAQ

Common questions about compounded hormone replacement therapy — answers for patients.

What is the difference between bioidentical and synthetic hormones?

Bioidentical hormones have the same molecular structure as certain hormones your body produces. Synthetic hormones have different molecular structures and may interact with receptors differently. Both are real options; the choice depends on your individual situation and your prescriber's plan.

Is bioidentical the same as compounded?

No. "Bioidentical" refers to molecular structure. "Compounded" refers to how the medication is prepared. Bioidentical hormones are available both as Health Canada‑approved commercial products and as compounded preparations. Compounded preparations allow customization when approved products don't meet a specific need.

Are compounded hormone preparations safer than approved hormone products?

This claim is sometimes made in marketing but isn't well‑supported by direct head‑to‑head evidence. Major medical organizations have generally not endorsed claims that compounded preparations are categorically safer. Your prescriber can discuss what fits your specific situation.

Do I need a prescription for a compounded hormone preparation?

Yes. Compounded hormone preparations are prescription‑only, like any prescription hormone therapy. You'll need a prescription from a licensed Ontario prescriber — a physician or nurse practitioner.

How do I find a prescriber who works with compounded hormone therapy?

Many family physicians and nurse practitioners are comfortable with hormone therapy. If your current provider isn't, ask for a referral to a gynecologist or menopause specialist. We don't maintain a list of recommended prescribers.

Are compounded hormone preparations covered by insurance?

Coverage varies by extended health plan and the specific ingredients. Some plans cover compounded preparations, others don't or cover them partially. We provide upfront pricing before preparing any compound and itemized receipts for insurance submission.

How much does a compounded hormone preparation cost?

Cost depends on the specific formulation — active ingredients, dose, vehicle, and quantity. We provide pricing in advance for each prescription. If a Health Canada–approved alternative would be more affordable and clinically appropriate, that's a discussion to have with your prescriber.

How quickly will hormone therapy work?

Effects are typically gradual. Most patients notice improvement within 2‑8 weeks. Full benefit often takes longer. If you're not noticing any change by 6 weeks, that's worth discussing with your prescriber.

What side effects can hormone therapy have?

Common early side effects (often transient): breast tenderness, bloating, mild mood changes, headaches. Less common but possible: skin reactions to topical preparations, irregular bleeding, changes in libido. More serious risks include venous thromboembolism, stroke, and breast cancer — risks vary by individual factors. Discuss specific concerns with your prescriber.

Can hormone creams transfer to others through skin contact?

Yes, transfer is possible if there's skin‑to‑skin contact at the application site shortly after application. Wait at least 30 minutes before close contact. Wash hands after application. This is particularly important if children, pets, or pregnant individuals are in close contact.

How long will I need to be on hormone therapy?

This is individual. Some patients use short‑term therapy for severe vasomotor symptoms; others continue longer‑term. Decisions about duration involve ongoing risk‑benefit discussion with your prescriber.

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